Emerging Cannabinoids: Beyond CBD and THC
For decades, the spotlight in cannabis research and medicine has focused on two main compounds: CBD (cannabidiol) and THC (tetrahydrocannabinol). But as science continues to explore the complexity of the cannabis plant, we’re learning there’s much more beneath the surface.
Enter the emerging cannabinoids — lesser-known compounds that may offer unique benefits, often without the intense psychoactivity of THC. Many of these cannabinoids are still being studied, but early research suggests they could play important roles in pain management, mood support, sleep, inflammation, and more.
Let’s take a closer look at what they are, where they stand in Australia, and why they’re worth watching.
What Are Cannabinoids?
Cannabinoids are naturally occurring compounds found in the cannabis plant. They interact with the endocannabinoid system (ECS) — a network of receptors in the human body involved in mood, sleep, pain, immune function, and more.
There are over 140 known cannabinoids, but most are present in tiny amounts. As extraction technology and breeding techniques improve, we’re gaining better access to these minor or rare cannabinoids — many of which were previously too difficult to isolate or study.
Meet the Emerging Cannabinoids
Here are some of the most promising cannabinoids gaining attention in the cannabis space:
1. CBN (Cannabinol)
Known for: Mild sedation, sleep support, anti-inflammatory properties
Psychoactive? Mildly, but far less than THC
CBN forms as THC oxidises and breaks down — which is why it’s often found in aged or heated cannabis. It’s being explored for insomnia, muscle relaxation, and anti-bacterial effects.
Often used in night-time blends. Early research suggests CBN may support sleep — especially when paired with CBD or THC.
2. CBG (Cannabigerol)
Known for: Focus, inflammation, gut health
Psychoactive? No
CBG is often called the “mother cannabinoid” because it’s the precursor to THC, CBD, and other cannabinoids. It’s being studied for its potential in:
- IBS and Crohn’s Disease
- Bladder dysfunction
- Neuroprotection
- Anti-bacterial action (including MRSA)
May have mood-stabilising and anti-inflammatory properties without sedation or high.
3. CBC (Cannabichromene)
Known for: Mood support, neurogenesis, inflammation
Psychoactive? No
CBC is being explored for its anti-inflammatory and antidepressant potential, as well as possible support for brain health and memory formation. It appears to work synergistically with CBD and THC to amplify effects — another example of the entourage effect.
Preliminary animal studies show potential for reducing pain and inflammation in combination with other cannabinoids.
4. THCV (Tetrahydrocannabivarin)
Known for: Appetite suppression, energy, blood sugar regulation
Psychoactive? Yes — but very different to THC
Unlike THC, THCV may reduce appetite, increase focus, and support metabolic balance. It’s being studied for type 2 diabetes, obesity, and even addiction-related behaviours.
Sometimes referred to as “diet weed” — but its therapeutic potential goes beyond weight control.
5. CBDV (Cannabidivarin)
Known for: Seizure support, neurodevelopmental research
Psychoactive? No
CBDV is structurally similar to CBD and is gaining interest for its potential in treating epilepsy, autism spectrum disorders, and neurological conditions. Clinical trials are ongoing globally.
May support brain signalling pathways involved in seizures and neurodiverse conditions.
What About Emerging Cannabinoids in Australia?
Most of these cannabinoids are not yet individually regulated, but if included in a formula with detectable THC or CBD, they are subject to the same scheduling laws — meaning prescription-only use under Schedule 4 or Schedule 8 of the Poisons Standard.
That said, many Australian patients are already using oils or capsules that contain low levels of CBG, CBC or CBN — naturally occurring as part of full spectrum or refined broad spectrum extracts.
These cannabinoids aren’t available as isolated products (yet), but they’re starting to appear in compound formulas via legally prescribed medicinal cannabis.
Why It Matters: Looking Beyond CBD and THC
Understanding the full range of cannabinoids allows for more targeted, personalised cannabis medicine.
As research expands and regulations evolve, we may one day see:
- Daytime blends rich in CBG for focus and clarity
- Night blends with CBD + CBN for sleep
- Low-dose THCV options for metabolic health
- Neuroprotective formulas featuring CBC and CBDV
This is the future of plant medicine: whole-plant potential, backed by science, and tailored to the individual.
What Should Consumers Know Now?
If you’re exploring medical cannabis in Australia, here’s what to keep in mind:
✅ Ask your doctor or pharmacist if your prescription contains minor cannabinoids
✅ Look for third-party testing (COAs) to confirm cannabinoid content
✅ Understand that full or broad spectrum oils may include more than just CBD and THC
✅ Avoid buying “rare cannabinoid” products from unregulated sources — they may be unsafe, mislabeled, or illegal
We’re only just beginning to understand what this incredible plant is capable of. While CBD and THC have laid the foundation, the next chapter in cannabis medicine belongs to the emerging cannabinoids — and to the people who keep asking questions, seeking alternatives, and advocating for access.
At Made In Hemp, we’re committed to helping Australians navigate this space with clarity, honesty, and hope for what’s ahead.